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Author:Kangdi 19-12-2021
What is glutathione?
Glutathione (glutathione, r-glutamyl cysteingl +glycine, GSH) is a tripeptide containing γ-amide bonds and sulfhydryl groups. It is composed of glutamic acid, cysteine and glycine. It exists in almost every part of the body. cell.
Glutathione can help maintain normal immune system function, and has antioxidant effects, integrated detoxification effects...etc.
Glutathione can be used not only in medicine, but also as a base material for functional foods. It is widely used in functional foods such as delaying aging, enhancing immunity, and anti-tumor. Well, seeing this, everyone knows, glutathione is not only a word mentioned by women, but men should also pay attention to it. After all, birth, old age, sickness and death are regardless of gender. Next look... Glutathione has two forms: reduced (G-SH) and oxidized (G-S-S-G). Under physiological conditions, reduced glutathione accounts for the majority. Glutathione reductase can catalyze the interconversion between the two types, and the coenzyme of this enzyme can also provide NADPH for the bypass metabolism of pentose phosphate. So now, let’s formally introduce glutathione:
Two different forms of glutathione
Active form of reduced glutathione (GSH) and inactive form of oxidized glutathione (GSSG). When glutathione patrols in the cell environment and extinguishes the oxidative "free radical" fire, it will be oxidized and lose its activity, thus becoming GSSG. Fortunately, due to an enzyme called glutathione reductase (GR), inactive GSSG can be recycled back to the active form of glutathione. When this enzyme is overwhelmed and too much oxidized GSSG accumulates (compared to active glutathione), the cell becomes vulnerable to damage.
The physiological functions of glutathione
1. Detoxification: Combining with poisons or drugs to eliminate its toxic effects; the sulfhydryl group on cysteine is its active group (so often abbreviated as G-SH), which is easy to combine with certain drugs, toxins, etc., so that it has Integrate detoxification.
2. Participate in redox reactions: as an important reducing agent, participate in a variety of redox reactions in the body;
3. Protect the activity of sulfhydrylase: keep the active group of sulfhydrylase—SH in a reduced state;
4. Maintain the stability of the red blood cell membrane structure: eliminate the damaging effect of oxidants on the red blood cell membrane structure.
The main application of glutathione
1. The clinical drug glutathione is widely used in clinics. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas and other toxins poisoning, it is also used in hepatitis, hemolytic diseases, keratitis, cataracts and retinal diseases, etc. Treatment or adjuvant therapy drugs. In recent years, Western scientists, especially Japanese scholars, have discovered that glutathione has the function of suppressing HIV. The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti-allergic effect, can also prevent skin aging and pigmentation, reduce the formation of melanin, improve the skin's antioxidant capacity and make the skin shiny, in addition , GSH also has a good effect in treating corneal diseases and improving sexual function.
2. Antioxidant effect Glutathione, as an important antioxidant in the body, can remove free radicals in the body; because GSH itself is susceptible to oxidation by certain substances, it can protect many proteins and enzymes in the body. The sulfhydryl groups are not oxidized by harmful substances, so as to ensure the normal performance of molecular physiological functions such as proteins and enzymes; the content of glutathione in human red blood cells is large, which is of great significance for protecting the sulfhydryl groups of proteins on the red blood cell membrane in a reduced state and preventing hemolysis.
3. Food additives Adding glutathione to food can play an unexpected role:
a. Adding to noodle products can play a reducing role. It not only shortens the time for making bread to one-half or one-third of the original, but also greatly improves the working conditions, and plays a role in strengthening food nutrition and other functions.
b. Add it to yogurt and baby food, equivalent to vitamin C, which can act as a stabilizer
c. Mix it into the fish cake to prevent the color from deepening.
d. Adding to meat products and cheese and other foods has the effect of intensifying flavor.
According to the physiological function of glutathione, Kandi has developed the glutathione patch, which is a whitening patch with good effect and no side effects. And We are able to customize all kinds of patches according to customers' formulation, existing brand name. We also offer the capabilities of formulating custom proprietary formulas for many different uses. Meanwhile, we are able to print your logo and your company information on the patches, packaging bag and box.
